Sudden, uncontrolled body movements and behavioral changes that are caused by abnormal electrical activity in the brain.
An epileptic seizure is a paroxysmal alteration that occurs in a person, abruptly and unexpectedly and usually ends quickly, due to an abnormal, sudden, brief and transient activity of the most important cells that make up the brain: neurons.
Epileptic seizures have a sudden onset and usually last seconds or a few minutes. During the epileptic seizure, the person may lose consciousness, have rhythmic movements or not and the person is not aware of anything, or on the contrary may remain conscious during the epileptic seizure and notice everything that happens, such as sudden involuntary movements, rhythmic or not, or an abnormal sensation, thought or emotion.
Some of the signs and symptoms of seizures:
To make the diagnosis, the health care provider will perform a physical examination. This includes a detailed examination of the brain and nervous system.
An EEG (electroencephalogram) will be done to check the electrical activity in the brain. People with epilepsy often have abnormal electrical activity seen on this test. In some cases, the test shows the area of the brain where seizures begin. The brain may appear normal after a seizure or between seizures.
Having seizures at certain times can lead to dangerous circumstances:
Intravenous MSC therapy is a valuable strategy to help epileptics who do not respond to anticonvulsant medications.
This procedure offers the possibility of seizure control and rescue of cognitive deficits in these patients, as GABAergic interneurons obtained from differentiating mesenchymal stem cells are effective in treating epilepsy caused by alterations in the GABAergic system of the brain.